The Skibbereen Poor Law Union was officially declared in 1839. The Workhouse was opened in 1842 at a cost of £8,300. It was built to house a maximum capacity of 800 inmates. The Skibbereen Workhouse was built to accomodate people from the areas of Abbeystowry, Aghadown, Ardfield, Caharragh, Castlehaven, Castrumventry, Creagh, Drinagh, Drumdaleague, Kilcoe, Kilfaughmabeg, Kilkerranmore, Kilmacabea, Kilmoe, Mycross, Rathbarry, Roscarbery, Schull, Tullagh, and Clear.
In 1921 the Skibbereen Workhouse was burned down by Republican forces.
The Skibbereen Workhouse site is now occupied by the local community hospital with only a small portion of the original buildings surviving.
Artist Toma McCullim worked with Staff and Residents of Skibbereen Hospital to create a public sculpture in the grounds of the hospital , the former workhouse , to commemorate the 110 girls who left the workhouse to be sent to Australia as part of the Earl Grey Scheme. It is sited on the old stone walls , at the former enterance to the women's section.